Killarney, Ireland – 10 November 2025 – ONCOassist®, the world’s leading oncology decision-support platform used by more than 100,000 oncology professionals across 180 countries, has announced the launch of ONCO-IQ, a new quiz-based learning feature that turns oncology education into an engaging, evidence-driven experience.

Designed specifically for oncologists, ONCO-IQ presents short, focused clinical quizzes covering the latest trial data, treatment updates, and evolving standards of care. Each quiz allows users to test their knowledge, view evidence-based explanations, and compare results with peers around the world—all within the trusted ONCOassist environment.

“With ONCO-IQ, we wanted to make learning in oncology more interactive, practical, and enjoyable,” said Eoin O’Carroll, CEO and Co-Founder of ONCOassist. “Clinicians are constantly faced with new data and changing guidelines. By transforming this information into concise, quiz-style challenges, we help oncology professionals stay sharp, confident, and informed—without adding to their workload.”

Kevin Bambury, Co-Founder and Chief Commercial Officer of ONCOassist, added:

“Pharma and medical education partners are increasingly looking for compliant, measurable ways to reach oncology professionals. ONCO-IQ delivers a science-driven, gamified format that encourages real engagement—allowing partners to support education and awareness initiatives while providing actionable analytics on knowledge uptake.”

Dr. Richard Bambury, Chief Medical Officer at ONCOassist, commented:

“As an oncologist, I know how valuable it is to test knowledge in real time. ONCO-IQ brings that opportunity directly into the clinician’s workflow—quick, evidence-based quizzes that reinforce understanding of the latest advances in cancer care. It’s an innovative way to support continuous learning while keeping the focus on patient outcomes.”

Built on ONCOassist’s CE-approved, evidence-based platform, ONCO-IQ offers a compliant, high-impact channel for pharmaceutical and medical-education partners to collaborate on oncology knowledge-reinforcement initiatives. Every quiz undergoes medical review to ensure scientific accuracy, educational integrity, and fair balance.

ONCO-IQ is now available to verified oncologists and physicians in the U.S. through the ONCOassist app and web platform. Access for oncology nurses and allied health professionals is planned for 2026.

About ONCOassist®

ONCOassist is a CE-approved clinical decision-support platform created by Portable Medical Technology Ltd. It provides oncology healthcare professionals with validated calculators, prognostic tools, toxicity management guidelines, staging criteria, and educational resources in one easy-to-use platform. ONCOassist partners with pharmaceutical companies, medical societies, and research organizations to advance oncology education and improve clinical decision-making globally.

Media Contact:
ONCOassist® – Media Relations 📧 eoin@portablemedicaltechnology.com
🌐 www.oncoassist.com

Your go-to digest for the latest breakthroughs in cancer care.

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Leading voices. Big insights. This episode of Oncology Spotlight delivers—scroll down to watch now!

Revolution Medicines Lands FDA Breakthrough for Daraxonrasib in KRAS G12‑Mutant Metastatic Pancreatic Cancer

The FDA has granted Breakthrough Therapy designation to Daraxonrasib, an oral RAS(ON) inhibitor, for previously treated metastatic pancreatic ductal adenocarcinoma (PDAC) with KRAS G12X mutations. In Phase 1 (RMC-6236-001), second‑line metastatic PDAC (progressed within six months of prior therapy), median PFS was 8.1 months (95% CI, 5.9–NE) for KRAS G12X and 7.6 months (95% CI, 5.3–NE) for all RAS‑mutated cases. For third‑line or later treatment with RMC‑6236, median PFS was 4.2 months (95% CI, 4.1–6.4). Among second‑line+ patients with KRAS G12X, ORR reached 20% (16/79) at ≥14 weeks and 27% (13/48) at ≥20 weeks, with a 14‑week DCR of 87%. 

The global Phase 3 RASolute‑302 trial is ongoing, comparing daraxonrasib to standard chemotherapy in G12X (plus expanded G13X and Q61X) cohorts, with dual primary endpoints of PFS and OS. Topline results are expected in 2026. (Reference: Revolution Medicines, Inc. “Revolution Medicines Announces FDA Breakthrough Therapy Designation for Daraxonrasib in Previously Treated Metastatic Pancreatic Cancer with KRAS G12 Mutations.” GlobeNewswire, 23 June 2025)

Amgen Reveals Positive Phase 3 Bemarituzumab Data in FGFR2b-positive Gastric Cancer

Amgen’s Phase III FORTITUDE‑101 trial met its primary endpoint, demonstrating a significant overall survival benefit when Bemarituzumab was added to mFOLFOX6 in FGFR2b-overexpressing, HER2-negative gastric or gastroesophageal junction cancer.
The 547-patient study selected tumors with ≥10% FGFR2b positivity; ocular events (like keratitis and vision changes) and hematologic toxicities were more common in the treatment arm. Detailed efficacy and safety data, along with results from an upcoming chemo+nivolumab combo study, are expected later this year. (Reference: Amgen Announces Positive Topline Phase 3 Results for Bemarituzumab in Fibroblast Growth Factor Receptor 2b (FGFR2b)‑Positive First‑Line Gastric Cancer.” Amgen Press Release, 30 June 2025.)

FDA Lifts REMS for CAR‑T Therapies

As of June 27, the FDA removed REMS requirements for all FDA-approved BCMA- and CD19-directed autologous CAR‑T therapies—Abecma, Breyanzi, Carvykti, Kymriah, Tecartus, and Yescarta .
Key changes:

• No facility certification or requirement for on-site tocilizumab
• Relaxed patient monitoring and location restrictions
• Supports broader application in community and rural centers 

(Reference: U.S. Food and Drug Administration. “FDA Eliminates Risk Evaluation and Mitigation Strategies (REMS) for Autologous Chimeric Antigen Receptor (CAR) T Cell Immunotherapies.” FDA Press Release, 27 June 2025.)

FDA Grants Accelerated Approval to Sunvozertinib (Zegfrovy) for EGFR Exon 20+ NSCLC

On July 2, 2025, the FDA granted accelerated approval to Sunvozertinib (Zegfrovy, Dizal (Jiangsu) Pharmaceutical Co., Ltd.) for adults with locally advanced or metastatic NSCLC harboring EGFR exon 20 insertion mutations, following disease progression on platinum-based chemotherapy.
In the WU‑KONG1B trial (n=85), sunvozertinib showed a 46% ORR and median duration of response of 11.1 months. The FDA also approved a companion diagnostic to identify eligible patients. (Reference: U.S. Food and Drug Administration. “FDA Grants Accelerated Approval to Sunvozertinib for Metastatic Non‑Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations.” FDA Press Release, 2 July 2025.)

Lynozyfic (Linvoseltamab‑gcpt) Joins Myeloma Armamentarium

The FDA granted accelerated approval to Linvoseltamab‑gcpt (Lynozyfic, Regeneron Pharmaceuticals, Inc.) on July 2, 2025, for adult patients with relapsed or refractory multiple myeloma after at least four prior lines of therapy, including a proteasome inhibitor, IMiD, and anti‑CD38 antibody.
In the LINKER‑MM1 trial, the BCNMA×CD3 engager achieved a 70% ORR, With a median follow-up of 11.3 months among responders, the estimated duration of response (DOR) was 89% (95% CI: 77, 95) at 9 months and 72% (95% CI: 54, 84) at 12 months. (Reference: U.S. Food and Drug Administration. “FDA Grants Accelerated Approval to Linvoseltamab‑gcpt for Relapsed or Refractory Multiple Myeloma.” FDA Press Release, 2 July 2025.)

This week’s Oncology Spotlight: Dr. Paul O’Brien’s Unconventional Journey into Medicine (Click here to watch)

Dr. Paul O’Brien’s journey—from food science to clinical medicine across China and Ireland now fuels his mission to combat medical misinformation. On Oncology Spotlight, he discusses resilience from his training, an open‑letter moment, AI in decision‑making, and the fight back against pseudoscience and viral influencers. His story is a powerful call for physicians to reclaim the social‑media narrative.

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