Oncology drug interaction checker
Patients on anti-cancer therapy often take many other medicines. The ONCOassist drug interaction checker lets oncology professionals check combinations of anti-cancer drugs, supportive-care medicines and common co-medications at the point of care, and see how serious each interaction is.
How it works
- Add two or more drugs by generic or brand name
- See each interaction with its severity
- Read the mechanism and suggested management
Why interactions matter in oncology
Drug interactions can alter anticancer drug exposure or compound adverse effects, potentially compromising treatment safety and efficacy. For example, itraconazole, a strong CYP3A inhibitor, increases palbociclib exposure and should generally be avoided during treatment. Combining ribociclib with QT-prolonging medicines can increase the risk of clinically significant QT prolongation and should also be avoided. Checking concomitant medicines against current prescribing information helps identify combinations requiring an alternative drug, dose adjustment or additional monitoring.
Check interactions in ONCOassist
Free for healthcare professionals on iOS, Android and the web.
Frequently asked questions
Can I check multiple medicines at the same time?
Yes. Add the medicines you want to check to review potential interactions between them in a single search.
Is it free?
Yes, for healthcare professionals.
This tool supports, and does not replace, clinical judgement and pharmacist review.
Medically reviewed by Dr. Lakshmi Ramachandran, MBBS (JIPMER, India), CCEPC, MD Radiation Oncology (JIPMER, India), Clinical Officer, ONCOassist. Last reviewed November 2026.